Cargando…

Comment on “On the Utility of ToxCast™ and ToxPi as Methods for Identifying New Obesogens”

Detalles Bibliográficos
Autores principales:	Houck, Keith A., Judson, Richard S., Knudsen, Thomas B., Martin, Matthew T., Richard, Ann M., Crofton, Kevin M., Simeonov, Anton, Paules, Richard S., Bucher, John R., Thomas, Russell S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Institute of Environmental Health Sciences 2017
Materias:	Correspondence
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226707/ https://www.ncbi.nlm.nih.gov/pubmed/28055944 http://dx.doi.org/10.1289/EHP881

Ejemplares similares

On the Utility of ToxCast™ and ToxPi as Methods for Identifying New Obesogens
por: Janesick, Amanda Shaine, et al.
Publicado: (2016)

Reply to “Comment on ‘On the Utility of ToxCast™ and ToxPi as Methods for Identifying New Obesogens’”
por: Janesick, Amanda S., et al.
Publicado: (2017)

Endocrine Profiling and Prioritization of Environmental Chemicals Using ToxCast Data
por: Reif, David M., et al.
Publicado: (2010)

Uncertainty quantification in ToxCast high throughput screening
por: Watt, Eric D., et al.
Publicado: (2018)

Using ToxCast™ Data to Reconstruct Dynamic Cell State Trajectories and Estimate Toxicological Points of Departure
por: Shah, Imran, et al.
Publicado: (2015)

In Vitro Screening of Environmental Chemicals for Targeted Testing Prioritization: The ToxCast Project
por: Judson, Richard S., et al.
Publicado: (2010)

Profiling 976 ToxCast Chemicals across 331 Enzymatic and Receptor Signaling Assays
por: Sipes, Nisha S., et al.
Publicado: (2013)

The ToxCast pipeline: updates to curve-fitting approaches and database structure
por: Feshuk, M., et al.
Publicado: (2023)

Potential of ToxCast Data in the Safety Assessment of Food Chemicals
por: Punt, Ans, et al.
Publicado: (2020)

ToxCast(™) Wants You: Recommendations for Engaging the Broader Scientific Community
por: Arnold, Carrie
Publicado: (2015)

Informing Selection of Nanomaterial Concentrations for ToxCast in Vitro Testing Based on Occupational Exposure Potential
por: Gangwal, Sumit, et al.
Publicado: (2011)

Prioritizing Environmental Chemicals for Obesity and Diabetes Outcomes Research: A Screening Approach Using ToxCast™ High-Throughput Data
por: Auerbach, Scott, et al.
Publicado: (2016)

ToxCast EPA in Vitro to in Vivo Challenge: Insight into the Rank-I Model
por: Novotarskyi, Sergii, et al.
Publicado: (2016)

Evaluation of Computational Docking to Identify Pregnane X Receptor Agonists in the ToxCast Database
por: Kortagere, Sandhya, et al.
Publicado: (2010)

ToxCast on Target: In Vitro Assays and Computer Modeling Show Promise for Screening Chemicals
por: Haynes, Rebecca Clay
Publicado: (2010)

QSAR modeling for In vitro assays: linking ToxCast™ database to the integrated modeling framework “OCHEM”
por: Abdelaziz, Ahmed, et al.
Publicado: (2012)

Investigating Molecular Mechanisms of Immunotoxicity and the Utility of ToxCast for Immunotoxicity Screening of Chemicals Added to Food
por: Naidenko, Olga V., et al.
Publicado: (2021)

On the Utility of ToxCast-Based Predictive Models to Evaluate Potential Metabolic Disruption by Environmental Chemicals
por: Filer, Dayne L., et al.
Publicado: (2022)

ToxCast chemical library Wnt screen identifies diethanolamine as an activator of neural progenitor proliferation
por: Wolter, Justin M., et al.
Publicado: (2022)

Characterizing the effects of missing data and evaluating imputation methods for chemical prioritization applications using ToxPi
por: To, Kimberly T., et al.
Publicado: (2018)

Comparison between endocrine activity assessed using ToxCast/Tox21 database and human plasma concentration of sunscreen active ingredients/UV filters
por: Onyango, David O, et al.
Publicado: (2023)

The Tox21 10K Compound Library: Collaborative Chemistry Advancing Toxicology
por: Richard, Ann M., et al.
Publicado: (2020)

ToxPi Graphical User Interface 2.0: Dynamic exploration, visualization, and sharing of integrated data models
por: Marvel, Skylar W., et al.
Publicado: (2018)

ToxPi*GIS Toolkit: Creating, viewing, and sharing integrative visualizations for geospatial data using ArcGIS
por: Fleming, Jonathon, et al.
Publicado: (2021)

ToxPi*GIS Toolkit: creating, viewing, and sharing integrative visualizations for geospatial data using ArcGIS
por: Fleming, Jonathon, et al.
Publicado: (2022)

High-throughput screening and chemotype-enrichment analysis of ToxCast phase II chemicals evaluated for human sodium-iodide symporter (NIS) inhibition
por: Wang, Jun, et al.
Publicado: (2019)

Developmental Effects of the ToxCast™ Phase I and Phase II Chemicals in Caenorhabditis elegans and Corresponding Responses in Zebrafish, Rats, and Rabbits
por: Boyd, Windy A., et al.
Publicado: (2015)

In silico identification of protein targets for chemical neurotoxins using ToxCast in vitro data and read-across within the QSAR toolbox
por: Chushak, Y. G., et al.
Publicado: (2018)

Editor’s Highlight: Screening ToxCast Prioritized Chemicals for PPARG Function in a Human Adipose-Derived Stem Cell Model of Adipogenesis
por: Foley, Briana, et al.
Publicado: (2017)

Screening ToxCast™ for Chemicals That Affect Cholesterol Biosynthesis: Studies in Cell Culture and Human Induced Pluripotent Stem Cell–Derived Neuroprogenitors
por: Wages, Phillip A., et al.
Publicado: (2020)

Analysis of structure–activity and structure–mechanism relationships among thyroid stimulating hormone receptor binding chemicals by leveraging the ToxCast library
por: Sahoo, Ajaya Kumar, et al.
Publicado: (2023)

Evaluation of OASIS QSAR Models Using ToxCast™ in Vitro Estrogen and Androgen Receptor Binding Data and Application in an Integrated Endocrine Screening Approach
por: Bhhatarai, Barun, et al.
Publicado: (2016)

Comprehensive Analyses and Prioritization of Tox21 10K Chemicals Affecting Mitochondrial Function by in-Depth Mechanistic Studies
por: Xia, Menghang, et al.
Publicado: (2018)

Atomistic Analysis of ToxN and ToxI Complex Unbinding Mechanism
por: Hu, Guodong, et al.
Publicado: (2018)

Profiling the Tox21 Chemical Collection for Acetylcholinesterase Inhibition
por: Li, Shuaizhang, et al.
Publicado: (2021)

Derivation of a Human In Vivo Benchmark Dose for Bisphenol A from ToxCast In Vitro Concentration Response Data Using a Computational Workflow for Probabilistic Quantitative In Vitro to In Vivo Extrapolation
por: Loizou, George, et al.
Publicado: (2022)

Derivation of a Human In Vivo Benchmark Dose for Perfluorooctanoic Acid From ToxCast In Vitro Concentration–Response Data Using a Computational Workflow for Probabilistic Quantitative In Vitro to In Vivo Extrapolation
por: Loizou, George, et al.
Publicado: (2021)

The periplasmic domains of Vibriocholerae ToxR and ToxS are forming a strong heterodimeric complex independent on the redox state of ToxR cysteines
por: Gubensäk, Nina, et al.
Publicado: (2021)

Profiling of the Tox21 10K compound library for agonists and antagonists of the estrogen receptor alpha signaling pathway
por: Huang, Ruili, et al.
Publicado: (2014)

Clinical Case—Rhus Tox
por: Potter, H. E.
Publicado: (1889)

Cannot write session to /tmp/vufind_sessions/sess_rk6elg5v6ai8sbifjcnjt9lokt