Chronic Colovesical Fistula Leading to Chronic Urinary Tract Infection Resulting in End-Stage Renal Disease in a Chronic Granulomatous Disease Patient

A 46-year old man with X-linked chronic granulomatous disease (CGD) being followed at the National Institute of Health with uncontrolled CGD colitis who developed chronic colovesical fistula, and end-stage renal disease (ESRD). Despite aggressive medical management of symptoms with immunomodulators...

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Autores principales: Siddiqui, M.R., Sanford, T., Nair, A., Zerbe, C.S., Hughes, M.S., Folio, L., Agarwal, Piyush K., Brancato, S.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Functional Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226852/
https://www.ncbi.nlm.nih.gov/pubmed/28083485
http://dx.doi.org/10.1016/j.eucr.2016.12.002
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author Siddiqui, M.R.
Sanford, T.
Nair, A.
Zerbe, C.S.
Hughes, M.S.
Folio, L.
Agarwal, Piyush K.
Brancato, S.J.
author_facet Siddiqui, M.R.
Sanford, T.
Nair, A.
Zerbe, C.S.
Hughes, M.S.
Folio, L.
Agarwal, Piyush K.
Brancato, S.J.
author_sort Siddiqui, M.R.
collection PubMed
description A 46-year old man with X-linked chronic granulomatous disease (CGD) being followed at the National Institute of Health with uncontrolled CGD colitis who developed chronic colovesical fistula, and end-stage renal disease (ESRD). Despite aggressive medical management of symptoms with immunomodulators and antibiotic prophylaxis, the chronic colovesical fistula led to chronic pyelonephritis, recurrent urinary tract infections, persistent air in the collecting system and bladder, and post-renal obstruction resulting in renal failure. Patient is now hemodialysis dependent and required diverting loop ileostomy placement. This report highlights multiple potential etiologies of rising serum creatinine in patients with CGD.
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spelling pubmed-52268522017-01-12 Chronic Colovesical Fistula Leading to Chronic Urinary Tract Infection Resulting in End-Stage Renal Disease in a Chronic Granulomatous Disease Patient Siddiqui, M.R. Sanford, T. Nair, A. Zerbe, C.S. Hughes, M.S. Folio, L. Agarwal, Piyush K. Brancato, S.J. Urol Case Rep Functional Medicine A 46-year old man with X-linked chronic granulomatous disease (CGD) being followed at the National Institute of Health with uncontrolled CGD colitis who developed chronic colovesical fistula, and end-stage renal disease (ESRD). Despite aggressive medical management of symptoms with immunomodulators and antibiotic prophylaxis, the chronic colovesical fistula led to chronic pyelonephritis, recurrent urinary tract infections, persistent air in the collecting system and bladder, and post-renal obstruction resulting in renal failure. Patient is now hemodialysis dependent and required diverting loop ileostomy placement. This report highlights multiple potential etiologies of rising serum creatinine in patients with CGD. Elsevier 2017-01-10 /pmc/articles/PMC5226852/ /pubmed/28083485 http://dx.doi.org/10.1016/j.eucr.2016.12.002 Text en http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Functional Medicine
Siddiqui, M.R.
Sanford, T.
Nair, A.
Zerbe, C.S.
Hughes, M.S.
Folio, L.
Agarwal, Piyush K.
Brancato, S.J.
Chronic Colovesical Fistula Leading to Chronic Urinary Tract Infection Resulting in End-Stage Renal Disease in a Chronic Granulomatous Disease Patient
title Chronic Colovesical Fistula Leading to Chronic Urinary Tract Infection Resulting in End-Stage Renal Disease in a Chronic Granulomatous Disease Patient
title_full Chronic Colovesical Fistula Leading to Chronic Urinary Tract Infection Resulting in End-Stage Renal Disease in a Chronic Granulomatous Disease Patient
title_fullStr Chronic Colovesical Fistula Leading to Chronic Urinary Tract Infection Resulting in End-Stage Renal Disease in a Chronic Granulomatous Disease Patient
title_full_unstemmed Chronic Colovesical Fistula Leading to Chronic Urinary Tract Infection Resulting in End-Stage Renal Disease in a Chronic Granulomatous Disease Patient
title_short Chronic Colovesical Fistula Leading to Chronic Urinary Tract Infection Resulting in End-Stage Renal Disease in a Chronic Granulomatous Disease Patient
title_sort chronic colovesical fistula leading to chronic urinary tract infection resulting in end-stage renal disease in a chronic granulomatous disease patient
topic Functional Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226852/
https://www.ncbi.nlm.nih.gov/pubmed/28083485
http://dx.doi.org/10.1016/j.eucr.2016.12.002
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