SUMOylation of the Hyperpolarization-Activated Cyclic Nucleotide-Gated Channel 2 Increases Surface Expression and the Maximal Conductance of the Hyperpolarization-Activated Current

Small Ubiquitin-like Modifier (SUMO) is a ∼10 kDa peptide that can be post-translationally added to a lysine (K) on a target protein to facilitate protein–protein interactions. Recent studies have found that SUMOylation can be regulated in an activity-dependent manner and that ion channel SUMOylatio...

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Detalles Bibliográficos
Autores principales: Parker, Anna R., Welch, Meghyn A., Forster, Lori A., Tasneem, Sarah M., Dubhashi, Janhavi A., Baro, Deborah J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226956/
https://www.ncbi.nlm.nih.gov/pubmed/28127275
http://dx.doi.org/10.3389/fnmol.2016.00168

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