CDK4/6 or MAPK blockade enhances efficacy of EGFR inhibition in oesophageal squamous cell carcinoma

Oesophageal squamous cell carcinoma is a deadly disease where systemic therapy has relied upon empiric chemotherapy despite the presence of genomic alterations pointing to candidate therapeutic targets, including recurrent amplification of the gene encoding receptor tyrosine kinase epidermal growth...

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Detalles Bibliográficos
Autores principales: Zhou, Jin, Wu, Zhong, Wong, Gabrielle, Pectasides, Eirini, Nagaraja, Ankur, Stachler, Matthew, Zhang, Haikuo, Chen, Ting, Zhang, Haisheng, Liu, Jie Bin, Xu, Xinsen, Sicinska, Ewa, Sanchez-Vega, Francisco, Rustgi, Anil K., Diehl, J. Alan, Wong, Kwok-Kin, Bass, Adam J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5227099/
https://www.ncbi.nlm.nih.gov/pubmed/28059068
http://dx.doi.org/10.1038/ncomms13897

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