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Structure of the cohesin loader Scc2

The functions of cohesin are central to genome integrity, chromosome organization and transcription regulation through its prevention of premature sister-chromatid separation and the formation of DNA loops. The loading of cohesin onto chromatin depends on the Scc2–Scc4 complex; however, little is kn...

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Detalles Bibliográficos
Autores principales: Chao, William C. H., Murayama, Yasuto, Muñoz, Sofía, Jones, Andrew W., Wade, Benjamin O., Purkiss, Andrew G., Hu, Xiao-Wen, Borg, Aaron, Snijders, Ambrosius P., Uhlmann, Frank, Singleton, Martin R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5227109/
https://www.ncbi.nlm.nih.gov/pubmed/28059076
http://dx.doi.org/10.1038/ncomms13952