CD8(+) T cells stimulate Na-Cl co-transporter NCC in distal convoluted tubules leading to salt-sensitive hypertension

Recent studies suggest a role for T lymphocytes in hypertension. However, whether T cells contribute to renal sodium retention and salt-sensitive hypertension is unknown. Here we demonstrate that T cells infiltrate into the kidney of salt-sensitive hypertensive animals. In particular, CD8(+) T cells...

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Detalles Bibliográficos
Autores principales: Liu, Yunmeng, Rafferty, Tonya M., Rhee, Sung W., Webber, Jessica S., Song, Li, Ko, Benjamin, Hoover, Robert S., He, Beixiang, Mu, Shengyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5227995/
https://www.ncbi.nlm.nih.gov/pubmed/28067240
http://dx.doi.org/10.1038/ncomms14037

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5227995/
https://www.ncbi.nlm.nih.gov/pubmed/28067240
http://dx.doi.org/10.1038/ncomms14037

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