CDK4/6-dependent activation of DUB3 regulates cancer metastasis through SNAIL1

Tumour metastasis, the spread of cancer cells from the original tumour site followed by growth of secondary tumours at distant organs, is the primary cause of cancer-related deaths and remains poorly understood. Here we demonstrate that inhibition of CDK4/6 blocks breast tumour metastasis in the tri...

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Detalles Bibliográficos
Autores principales: Liu, Tongzheng, Yu, Jia, Deng, Min, Yin, Yujiao, Zhang, Haoxing, Luo, Kuntian, Qin, Bo, Li, Yunhui, Wu, Chenming, Ren, Tao, Han, Yang, Yin, Peng, Kim, JungJin, Lee, SeungBaek, Lin, Jing, Zhang, Lizhi, Zhang, Jun, Nowsheen, Somaira, Wang, Liewei, Boughey, Judy, Goetz, Matthew P., Yuan, Jian, Lou, Zhenkun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5228031/
https://www.ncbi.nlm.nih.gov/pubmed/28067227
http://dx.doi.org/10.1038/ncomms13923

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