Pyruvate kinase type M2 promotes tumour cell exosome release via phosphorylating synaptosome-associated protein 23

Tumour cells secrete exosomes that are involved in the remodelling of the tumour–stromal environment and promoting malignancy. The mechanisms governing tumour exosome release, however, remain incompletely understood. Here we show that tumour cell exosomes secretion is controlled by pyruvate kinase t...

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Detalles Bibliográficos
Autores principales: Wei, Yao, Wang, Dong, Jin, Fangfang, Bian, Zhen, Li, Limin, Liang, Hongwei, Li, Mingzhen, Shi, Lei, Pan, Chaoyun, Zhu, Dihan, Chen, Xi, Hu, Gang, Liu, Yuan, Zhang, Chen-Yu, Zen, Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5228053/
https://www.ncbi.nlm.nih.gov/pubmed/28067230
http://dx.doi.org/10.1038/ncomms14041

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