Cargando…

Intracellular shuttling of a Drosophila APC tumour suppressor homolog

BACKGROUND: The Adenomatous polyposis coli (APC) tumour suppressor is found in multiple discrete subcellular locations, which may reflect sites of distinct functions. In Drosophila epithelial cells, the predominant APC relative (E-APC) is concentrated at the apicolateral adherens junctions. Genetic...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cliffe, Adam, Mieszczanek, Julius, Bienz, Mariann
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2004
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC522808/ https://www.ncbi.nlm.nih.gov/pubmed/15458577 http://dx.doi.org/10.1186/1471-2121-5-37

Ejemplares similares

The Adenomatous polyposis coli tumour suppressor is essential for Axin complex assembly and function and opposes Axin's interaction with Dishevelled
por: Mendoza-Topaz, Carolina, et al.
Publicado: (2011)

Bcl9 and Pygo synergise downstream of Apc to effect intestinal neoplasia in FAP mouse models
por: Mieszczanek, Juliusz, et al.
Publicado: (2019)

Wnt-Dependent Inactivation of the Groucho/TLE Co-repressor by the HECT E3 Ubiquitin Ligase Hyd/UBR5
por: Flack, Joshua E., et al.
Publicado: (2017)

Frequent Promoter Hypermethylation of the APC and RASSF1A Tumour Suppressors in Parathyroid Tumours
por: Juhlin, C. Christofer, et al.
Publicado: (2010)

Feedback control of Wnt signaling based on ultrastable histidine cluster co-aggregation between Naked/NKD and Axin
por: Gammons, Melissa V, et al.
Publicado: (2020)

Disinhibition of the HECT E3 ubiquitin ligase WWP2 by polymerized Dishevelled
por: Mund, Thomas, et al.
Publicado: (2015)

Constitutive scaffolding of multiple Wnt enhanceosome components by Legless/BCL9
por: van Tienen, Laurens M, et al.
Publicado: (2017)

Correction: Constitutive scaffolding of multiple Wnt enhanceosome components by Legless/BCL9
por: van Tienen, Laurens M, et al.
Publicado: (2017)

An ancient Pygo-dependent Wnt enhanceosome integrated by Chip/LDB-SSDP
por: Fiedler, Marc, et al.
Publicado: (2015)

Selective function of the PDZ domain of Dishevelled in noncanonical Wnt signalling
por: Mieszczanek, Juliusz, et al.
Publicado: (2022)

Intracellular Shuttle: The Lactate Aerobic Metabolism
por: Cruz, Rogério Santos de Oliveira, et al.
Publicado: (2012)

The tumour suppressor APC promotes HIV-1 assembly via interaction with Gag precursor protein
por: Miyakawa, Kei, et al.
Publicado: (2017)

Chronic Trichuris muris infection causes neoplastic change in the intestine and exacerbates tumour formation in APC min/+ mice
por: Hayes, Kelly S., et al.
Publicado: (2017)

Evolutionary Adaptation of the Fly Pygo PHD Finger toward Recognizing Histone H3 Tail Methylated at Arginine 2
por: Miller, Thomas C.R., et al.
Publicado: (2013)

Tumour Suppressor Adenomatous Polyposis Coli (APC) localisation is regulated by both Kinesin-1 and Kinesin-2
por: Ruane, Peter T., et al.
Publicado: (2016)

Decoding of Methylated Histone H3 Tail by the Pygo-BCL9 Wnt Signaling Complex
por: Fiedler, Marc, et al.
Publicado: (2008)

Bunched, the Drosophila homolog of the mammalian tumor suppressor TSC-22, promotes cellular growth
por: Gluderer, Silvia, et al.
Publicado: (2008)

A role for the p53 tumour suppressor in regulating the balance between homologous recombination and non-homologous end joining
por: Moureau, Sylvie, et al.
Publicado: (2016)

Characterizing Variants of Unknown Significance of the PTEN tumour suppressorHomolog DAF-18
por: Ermakova, Glafira, et al.
Publicado: (2022)

Transcriptional repression of Myc underlies the tumour suppressor function of AGO1 in Drosophila
por: Zaytseva, Olga, et al.
Publicado: (2020)

The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1
por: Harris, Lee D., et al.
Publicado: (2021)

The tumor suppressor Apc controls planar cell polarities central to gut homeostasis
por: Bellis, Julien, et al.
Publicado: (2012)

Frequent Alteration of the Tumor Suppressor Gene APC in Sporadic Canine Colorectal Tumors
por: Youmans, Lydia, et al.
Publicado: (2012)

Genetic Systems to Investigate Regulation of Oncogenes and Tumour Suppressor Genes in Drosophila
por: Lee, Jue Er Amanda, et al.
Publicado: (2012)

Silencing the intestinal GUCY2C tumor suppressor axis requires APC loss of heterozygosity
por: Pattison, Amanda M., et al.
Publicado: (2020)

The novel tumour suppressor Madm regulates stem cell competition in the Drosophila testis
por: Singh, Shree Ram, et al.
Publicado: (2016)

Lifespan extension by increased expression of the Drosophila homologue of the IGFBP7 tumour suppressor
por: Alic, Nazif, et al.
Publicado: (2011)

Vps28 Is Involved in the Intracellular Trafficking of Awd, the Drosophila Homolog of NME1/2
por: Mezzofanti, Elisa, et al.
Publicado: (2019)

Intracellular Protein Shuttling: A Mechanism Relevant for Myelin Repair in Multiple Sclerosis?
por: Göttle, Peter, et al.
Publicado: (2015)

Axin phosphorylation in both Wnt-off and Wnt-on states requires the tumor suppressor APC
por: Tacchelly-Benites, Ofelia, et al.
Publicado: (2018)

A Targeted Constitutive Mutation in the Apc Tumor Suppressor Gene Underlies Mammary But Not Intestinal Tumorigenesis
por: Gaspar, Claudia, et al.
Publicado: (2009)

pBFK, a new thermosensitive shuttle vector for Streptococcus pyogenes gene deletion by homologous recombination
por: Boukthir, S., et al.
Publicado: (2023)

Photochemical Treatment of Drosophila APCs Can Eliminate Associated Viruses and Maintain the APC Function for Generating Antigen-Specific CTLs Ex Vivo
por: Ye, Jun, et al.
Publicado: (2018)

SR proteins: To shuttle or not to shuttle, that is the question
por: Hammarskjold, Marie-Louise, et al.
Publicado: (2017)

lemmingA encodes the Apc11 subunit of the APC/C in Drosophila melanogaster that forms a ternary complex with the E2-C type ubiquitin conjugating enzyme, Vihar and Morula/Apc2
por: Nagy, Olga, et al.
Publicado: (2012)

Notch signaling during development requires the function of awd, the Drosophila homolog of human metastasis suppressor gene Nm23
por: Ignesti, Marilena, et al.
Publicado: (2014)

The Relationship between the Methylation of Promoter Regions of Tumor Suppressor Genes PTEN and APC with Endometrial Cancer
por: Ghazanfari, Tayebeh, et al.
Publicado: (2019)

APC-β-catenin-TCF signaling silences the intestinal guanylin-GUCY2C tumor suppressor axis
por: Blomain, Erik S., et al.
Publicado: (2020)

The Human Homolog of Drosophila Headcase Acts as a Tumor Suppressor through Its Blocking Effect on the Cell Cycle in Hepatocellular Carcinoma
por: Wang, Jun, et al.
Publicado: (2015)

Infection with genotoxin‐producing Salmonella enterica synergises with loss of the tumour suppressor APC in promoting genomic instability via the PI3K pathway in colonic epithelial cells
por: Martin, Océane C.B., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_qut528g6slv4q25i088g4v223m