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Transcriptome and network analyses in Saccharomyces cerevisiae reveal that amphotericin B and lactoferrin synergy disrupt metal homeostasis and stress response

Invasive fungal infections are difficult to treat. The few available antifungal drugs have problems with toxicity or efficacy, and resistance is increasing. To overcome these challenges, existing therapies may be enhanced by synergistic combination with another agent. Previously, we found amphoteric...

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Detalles Bibliográficos
Autores principales: Pang, Chi Nam Ignatius, Lai, Yu-Wen, Campbell, Leona T., Chen, Sharon C.-A., Carter, Dee A., Wilkins, Marc R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5228129/
https://www.ncbi.nlm.nih.gov/pubmed/28079179
http://dx.doi.org/10.1038/srep40232