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Transcriptome and network analyses in Saccharomyces cerevisiae reveal that amphotericin B and lactoferrin synergy disrupt metal homeostasis and stress response
Invasive fungal infections are difficult to treat. The few available antifungal drugs have problems with toxicity or efficacy, and resistance is increasing. To overcome these challenges, existing therapies may be enhanced by synergistic combination with another agent. Previously, we found amphoteric...
Autores principales: | Pang, Chi Nam Ignatius, Lai, Yu-Wen, Campbell, Leona T., Chen, Sharon C.-A., Carter, Dee A., Wilkins, Marc R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5228129/ https://www.ncbi.nlm.nih.gov/pubmed/28079179 http://dx.doi.org/10.1038/srep40232 |
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