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Blood Occludin Level as a Potential Biomarker for Early Blood Brain Barrier Damage Following Ischemic Stroke

Concern about intracerebral hemorrhage (ICH) is the primary reason for withholding tPA therapy from patients with ischemic stroke. Early blood brain barrier (BBB) damage is the major risk factor for fatal post-thrombolysis ICH, but rapidly assessing BBB damage before tPA administration is highly cha...

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Detalles Bibliográficos
Autores principales: Pan, Rong, Yu, Kewei, Weatherwax, Theodore, Zheng, Handong, Liu, Wenlan, Liu, Ke Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5228160/
https://www.ncbi.nlm.nih.gov/pubmed/28079139
http://dx.doi.org/10.1038/srep40331