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Downregulation of miR-221/222 by a microRNA sponge promotes apoptosis in oral squamous cell carcinoma cells through upregulation of PTEN

MicroRNA-221 and microRNA-222 (miR-221/222) have been identified as oncogenes and confirmed to be overexpressed in various types of cancer. However, the regulation mechanism of miR-221/222 in oral squamous cell carcinoma (OSCC) remains to be fully elucidated. Previously, an miR-221/222 sponge was su...

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Detalles Bibliográficos
Autores principales: Zhou, Lijie, Jiang, Fangfang, Chen, Xijuan, Liu, Zifeng, Ouyang, Ying, Zhao, Wei, Yu, Dongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5228168/
https://www.ncbi.nlm.nih.gov/pubmed/28101204
http://dx.doi.org/10.3892/ol.2016.5250

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