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A mucin-like peptide from Fasciola hepatica instructs dendritic cells with parasite specific Th1-polarizing activity

Fasciolosis is a trematode zoonosis of interest in public health and cattle production. We report here the immunostimulatory effect of a 66 mer mucin-like peptide from Fasciola hepatica (Fhmuc), which synergizes with lipopolysaccharide (LPS) to promote dendritic cell (DC) maturation, endowing these...

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Detalles Bibliográficos
Autores principales: Noya, Verónica, Brossard, Natalie, Rodríguez, Ernesto, Dergan-Dylon, L. Sebastián, Carmona, Carlos, Rabinovich, Gabriel A., Freire, Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5228188/
https://www.ncbi.nlm.nih.gov/pubmed/28079156
http://dx.doi.org/10.1038/srep40615