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Evaluating the cytotoxicity of innate immune effector cells using the GrB ELISPOT assay

BACKGROUND: This study assessed the Granzyme B (GrB) ELISPOT as a viable alternative to the (51)Cr-release assay for measuring cytotoxic activity of innate immune effector cells. We strategically selected the GrB ELISPOT assay because GrB is a hallmark effector molecule of cell-mediated destruction...

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Detalles Bibliográficos
Autores principales:	Shafer-Weaver, Kimberly A, Sayers, Thomas, Kuhns, Douglas B, Strobl, Susan L, Burkett, Mark W, Baseler, Michael, Malyguine, Anatoli
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2004
Materias:	Methodology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC522821/ https://www.ncbi.nlm.nih.gov/pubmed/15380049 http://dx.doi.org/10.1186/1479-5876-2-31

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