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The value of 64-slice spiral CT perfusion imaging in the treatment of liver cancer with argon-helium cryoablation

We analyzed the effectiveness of using 64-slice spiral computed tomography (CT) and perfusion imaging to guide argon-helium cryoablation treatment of liver cancer. In total, 60 cases of advanced hepatocellular carcinoma before surgery treated with argon-helium cryoablation were inlcuded in the prese...

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Autores principales: Lv, Yinggang, Jin, Yurong, Yan, Qiaohuan, Yuan, Dingling, Wang, Yanling, Li, Xianping, Shen, Yanfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5228367/
https://www.ncbi.nlm.nih.gov/pubmed/28105165
http://dx.doi.org/10.3892/ol.2016.5241
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author Lv, Yinggang
Jin, Yurong
Yan, Qiaohuan
Yuan, Dingling
Wang, Yanling
Li, Xianping
Shen, Yanfeng
author_facet Lv, Yinggang
Jin, Yurong
Yan, Qiaohuan
Yuan, Dingling
Wang, Yanling
Li, Xianping
Shen, Yanfeng
author_sort Lv, Yinggang
collection PubMed
description We analyzed the effectiveness of using 64-slice spiral computed tomography (CT) and perfusion imaging to guide argon-helium cryoablation treatment of liver cancer. In total, 60 cases of advanced hepatocellular carcinoma before surgery treated with argon-helium cryoablation were inlcuded in the present study. Retrospective summary of the 60 cases of metaphase and advanced liver cancer were used as the control group. The control group were treated using cryoablation with argon-helium knife. We used enhanced scanning with 64-slice spiral CT to define the extent of their lesions and prepared a plan of percutaneous cryoablation for the treatment. Intraoperatively, we used the dynamics of CT perfusion imaging to observe the frozen ablation range and decreased the rate of complications. After surgery, the patients were followed-up regularly by 64-slice CT. We used conventional X-ray, CT and magnetic resonance imaging (MRI) for pre-operative lateralization. Intraoperative X-ray or ultrasound guidance and follow-up with CT or MTI were added to determine the clinical effectiveness and prognosis. The results showed that the total effective rate was improved significantly and incidence rate of overall complications decreased markedly in the observation group. Following treatment, AFP decreased significantly while the total freezing area and time were reduced significantly. The median survival time was increased significantly in the observation group. The numeric values of hepatic arterial perfusion, portal vein perfusion and hepatic arterial perfusion index were all markedly lowered after treatment. Differences were statistically significant (P<0.05). In conclusion, the use of 64-slice spiral CT perfusion imaging may considerably improve the effects of liver cancer treatment using the argon-helium cryoablation. It extended the survival time and reduced complications.
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spelling pubmed-52283672017-01-19 The value of 64-slice spiral CT perfusion imaging in the treatment of liver cancer with argon-helium cryoablation Lv, Yinggang Jin, Yurong Yan, Qiaohuan Yuan, Dingling Wang, Yanling Li, Xianping Shen, Yanfeng Oncol Lett Articles We analyzed the effectiveness of using 64-slice spiral computed tomography (CT) and perfusion imaging to guide argon-helium cryoablation treatment of liver cancer. In total, 60 cases of advanced hepatocellular carcinoma before surgery treated with argon-helium cryoablation were inlcuded in the present study. Retrospective summary of the 60 cases of metaphase and advanced liver cancer were used as the control group. The control group were treated using cryoablation with argon-helium knife. We used enhanced scanning with 64-slice spiral CT to define the extent of their lesions and prepared a plan of percutaneous cryoablation for the treatment. Intraoperatively, we used the dynamics of CT perfusion imaging to observe the frozen ablation range and decreased the rate of complications. After surgery, the patients were followed-up regularly by 64-slice CT. We used conventional X-ray, CT and magnetic resonance imaging (MRI) for pre-operative lateralization. Intraoperative X-ray or ultrasound guidance and follow-up with CT or MTI were added to determine the clinical effectiveness and prognosis. The results showed that the total effective rate was improved significantly and incidence rate of overall complications decreased markedly in the observation group. Following treatment, AFP decreased significantly while the total freezing area and time were reduced significantly. The median survival time was increased significantly in the observation group. The numeric values of hepatic arterial perfusion, portal vein perfusion and hepatic arterial perfusion index were all markedly lowered after treatment. Differences were statistically significant (P<0.05). In conclusion, the use of 64-slice spiral CT perfusion imaging may considerably improve the effects of liver cancer treatment using the argon-helium cryoablation. It extended the survival time and reduced complications. D.A. Spandidos 2016-12 2016-10-11 /pmc/articles/PMC5228367/ /pubmed/28105165 http://dx.doi.org/10.3892/ol.2016.5241 Text en Copyright: © Lv et al. This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (https://creativecommons.org/licenses/by-nc-nd/4.0/) , which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
spellingShingle Articles
Lv, Yinggang
Jin, Yurong
Yan, Qiaohuan
Yuan, Dingling
Wang, Yanling
Li, Xianping
Shen, Yanfeng
The value of 64-slice spiral CT perfusion imaging in the treatment of liver cancer with argon-helium cryoablation
title The value of 64-slice spiral CT perfusion imaging in the treatment of liver cancer with argon-helium cryoablation
title_full The value of 64-slice spiral CT perfusion imaging in the treatment of liver cancer with argon-helium cryoablation
title_fullStr The value of 64-slice spiral CT perfusion imaging in the treatment of liver cancer with argon-helium cryoablation
title_full_unstemmed The value of 64-slice spiral CT perfusion imaging in the treatment of liver cancer with argon-helium cryoablation
title_short The value of 64-slice spiral CT perfusion imaging in the treatment of liver cancer with argon-helium cryoablation
title_sort value of 64-slice spiral ct perfusion imaging in the treatment of liver cancer with argon-helium cryoablation
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5228367/
https://www.ncbi.nlm.nih.gov/pubmed/28105165
http://dx.doi.org/10.3892/ol.2016.5241
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