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Pulmonary intravascular large B-cell lymphoma successfully treated with rituximab, cyclophosphamide, vincristine, doxorubicin and prednisolone immunochemotherapy: Report of a patient surviving for over 1 year
A 73-year-old man with a history of lethargy, fever and dyspnea was admitted to Tottori University Hospital. A computed tomography (CT) scan revealed splenomegaly and diffusely spreading ground-glass opacities (GGOs) in both lungs. A video-assisted thoracoscopic surgery (VATS)-guided lung biopsy rev...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5228415/ https://www.ncbi.nlm.nih.gov/pubmed/28105347 http://dx.doi.org/10.3892/mco.2016.1063 |
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author | Nishii-Ito, Shizuka Izumi, Hiroki Touge, Hirokazu Takeda, Kenichi Hosoda, Yuzuru Yamasaki, Akira Kuwamoto, Satoshi Shimizu, Eiji Motokura, Toru |
author_facet | Nishii-Ito, Shizuka Izumi, Hiroki Touge, Hirokazu Takeda, Kenichi Hosoda, Yuzuru Yamasaki, Akira Kuwamoto, Satoshi Shimizu, Eiji Motokura, Toru |
author_sort | Nishii-Ito, Shizuka |
collection | PubMed |
description | A 73-year-old man with a history of lethargy, fever and dyspnea was admitted to Tottori University Hospital. A computed tomography (CT) scan revealed splenomegaly and diffusely spreading ground-glass opacities (GGOs) in both lungs. A video-assisted thoracoscopic surgery (VATS)-guided lung biopsy revealed intravascular proliferation of large atypical lymphoid cells in the arteries, veins and alveolar walls. The patient was diagnosed with intravascular large B-cell lymphoma (IVLBCL); he received 6 cycles of rituximab, cyclophosphamide, doxorubicin, vincristine and prednisolone (R-CHOP) immunochemotherapy and has remained in complete remission for >1 year. Although IVLBCL is a rare disease, it should be considered in the differential diagnosis of pulmonary diffuse lesions that present with GGOs on CT scans. |
format | Online Article Text |
id | pubmed-5228415 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | D.A. Spandidos |
record_format | MEDLINE/PubMed |
spelling | pubmed-52284152017-01-19 Pulmonary intravascular large B-cell lymphoma successfully treated with rituximab, cyclophosphamide, vincristine, doxorubicin and prednisolone immunochemotherapy: Report of a patient surviving for over 1 year Nishii-Ito, Shizuka Izumi, Hiroki Touge, Hirokazu Takeda, Kenichi Hosoda, Yuzuru Yamasaki, Akira Kuwamoto, Satoshi Shimizu, Eiji Motokura, Toru Mol Clin Oncol Articles A 73-year-old man with a history of lethargy, fever and dyspnea was admitted to Tottori University Hospital. A computed tomography (CT) scan revealed splenomegaly and diffusely spreading ground-glass opacities (GGOs) in both lungs. A video-assisted thoracoscopic surgery (VATS)-guided lung biopsy revealed intravascular proliferation of large atypical lymphoid cells in the arteries, veins and alveolar walls. The patient was diagnosed with intravascular large B-cell lymphoma (IVLBCL); he received 6 cycles of rituximab, cyclophosphamide, doxorubicin, vincristine and prednisolone (R-CHOP) immunochemotherapy and has remained in complete remission for >1 year. Although IVLBCL is a rare disease, it should be considered in the differential diagnosis of pulmonary diffuse lesions that present with GGOs on CT scans. D.A. Spandidos 2016-12 2016-10-26 /pmc/articles/PMC5228415/ /pubmed/28105347 http://dx.doi.org/10.3892/mco.2016.1063 Text en Copyright: © Nishii-Ito et al. This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (https://creativecommons.org/licenses/by-nc-nd/4.0/) , which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made. |
spellingShingle | Articles Nishii-Ito, Shizuka Izumi, Hiroki Touge, Hirokazu Takeda, Kenichi Hosoda, Yuzuru Yamasaki, Akira Kuwamoto, Satoshi Shimizu, Eiji Motokura, Toru Pulmonary intravascular large B-cell lymphoma successfully treated with rituximab, cyclophosphamide, vincristine, doxorubicin and prednisolone immunochemotherapy: Report of a patient surviving for over 1 year |
title | Pulmonary intravascular large B-cell lymphoma successfully treated with rituximab, cyclophosphamide, vincristine, doxorubicin and prednisolone immunochemotherapy: Report of a patient surviving for over 1 year |
title_full | Pulmonary intravascular large B-cell lymphoma successfully treated with rituximab, cyclophosphamide, vincristine, doxorubicin and prednisolone immunochemotherapy: Report of a patient surviving for over 1 year |
title_fullStr | Pulmonary intravascular large B-cell lymphoma successfully treated with rituximab, cyclophosphamide, vincristine, doxorubicin and prednisolone immunochemotherapy: Report of a patient surviving for over 1 year |
title_full_unstemmed | Pulmonary intravascular large B-cell lymphoma successfully treated with rituximab, cyclophosphamide, vincristine, doxorubicin and prednisolone immunochemotherapy: Report of a patient surviving for over 1 year |
title_short | Pulmonary intravascular large B-cell lymphoma successfully treated with rituximab, cyclophosphamide, vincristine, doxorubicin and prednisolone immunochemotherapy: Report of a patient surviving for over 1 year |
title_sort | pulmonary intravascular large b-cell lymphoma successfully treated with rituximab, cyclophosphamide, vincristine, doxorubicin and prednisolone immunochemotherapy: report of a patient surviving for over 1 year |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5228415/ https://www.ncbi.nlm.nih.gov/pubmed/28105347 http://dx.doi.org/10.3892/mco.2016.1063 |
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