Activation of AMP-activated protein kinase rapidly suppresses multiple pro-inflammatory pathways in adipocytes including IL-1 receptor-associated kinase-4 phosphorylation

Inflammation of adipose tissue in obesity is associated with increased IL-1β, IL-6 and TNF-α secretion and proposed to contribute to insulin resistance. AMP-activated protein kinase (AMPK) regulates nutrient metabolism and is reported to have anti-inflammatory actions in adipose tissue, yet the mech...

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Detalles Bibliográficos
Autores principales: Mancini, Sarah J., White, Anna D., Bijland, Silvia, Rutherford, Claire, Graham, Delyth, Richter, Erik A., Viollet, Benoit, Touyz, Rhian M., Palmer, Timothy M., Salt, Ian P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: North Holland Publishing 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5228585/
https://www.ncbi.nlm.nih.gov/pubmed/27840174
http://dx.doi.org/10.1016/j.mce.2016.11.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5228585/
https://www.ncbi.nlm.nih.gov/pubmed/27840174
http://dx.doi.org/10.1016/j.mce.2016.11.010

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