Cargando…

Untangling Basal Ganglia Network Dynamics and Function: Role of Dopamine Depletion and Inhibition Investigated in a Spiking Network Model

The basal ganglia are a crucial brain system for behavioral selection, and their function is disturbed in Parkinson’s disease (PD), where neurons exhibit inappropriate synchronization and oscillations. We present a spiking neural model of basal ganglia including plausible details on synaptic dynamic...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lindahl, Mikael, Hellgren Kotaleski, Jeanette
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Society for Neuroscience 2017
Materias:	New Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5228592/ https://www.ncbi.nlm.nih.gov/pubmed/28101525 http://dx.doi.org/10.1523/ENEURO.0156-16.2016

Ejemplares similares

Transient Response of Basal Ganglia Network in Healthy and Low-Dopamine State
por: Chakravarty, Kingshuk, et al.
Publicado: (2022)

Short term plasticity within the basal ganglia - a systems level computational investigation
por: Lindahl, Mikael, et al.
Publicado: (2011)

Functional Relevance of Different Basal Ganglia Pathways Investigated in a Spiking Model with Reward Dependent Plasticity
por: Berthet, Pierre, et al.
Publicado: (2016)

The Arbitration–Extension Hypothesis: A Hierarchical Interpretation of the Functional Organization of the Basal Ganglia
por: Kamali Sarvestani, Iman, et al.
Publicado: (2011)

Homologous Basal Ganglia Network Models in Physiological and Parkinsonian Conditions
por: Bahuguna, Jyotika, et al.
Publicado: (2017)

Signal enhancement in the output stage of the basal ganglia by synaptic short-term plasticity in the direct, indirect, and hyperdirect pathways
por: Lindahl, Mikael, et al.
Publicado: (2013)

Action selection performance of a reconfigurable basal ganglia inspired model with Hebbian–Bayesian Go-NoGo connectivity
por: Berthet, Pierre, et al.
Publicado: (2012)

Untangling Cortico-Striatal Connectivity and Cross-Frequency Coupling in L-DOPA-Induced Dyskinesia
por: Belić, Jovana J., et al.
Publicado: (2016)

Basal Ganglia Neuromodulation Over Multiple Temporal and Structural Scales—Simulations of Direct Pathway MSNs Investigate the Fast Onset of Dopaminergic Effects and Predict the Role of Kv4.2
por: Lindroos, Robert, et al.
Publicado: (2018)

Learning mechanisms for DA-modulated spiking networks in the basal ganglia
por: Vogt, Simon M, et al.
Publicado: (2010)

Mechanisms of Network Interactions for Flexible Cortico-Basal Ganglia-Mediated Action Control
por: Fischer, Petra
Publicado: (2021)

Dopamine depletion leads to pathological synchronization of distinct basal ganglia loops in the beta band
por: Ortone, Andrea, et al.
Publicado: (2023)

A spiking network model of basal ganglia to study the effect of dopamine medication and STN-DBS during probabilistic learning task
por: Mandali, Alekhya, et al.
Publicado: (2015)

The role of cortical oscillations in a spiking neural network model of the basal ganglia
por: Fountas, Zafeirios, et al.
Publicado: (2017)

Interplay between periodic stimulation and GABAergic inhibition in striatal network oscillations
por: Belić, Jovana J., et al.
Publicado: (2017)

Endocannabinoids and Dopamine Balance Basal Ganglia Output
por: Gorodetski, Lilach, et al.
Publicado: (2021)

Correction: The role of cortical oscillations in a spiking neural network model of the basal ganglia
por: Fountas, Zafeirios, et al.
Publicado: (2018)

Role of DARPP-32 and ARPP-21 in the Emergence of Temporal Constraints on Striatal Calcium and Dopamine Integration
por: Nair, Anu G., et al.
Publicado: (2016)

Beta synchrony in the cortico-basal ganglia network during regulation of force control on and off dopamine
por: Fischer, Petra, et al.
Publicado: (2019)

Neuronal avalanches and the cortico-striatal network
por: Belić, Jovana J, et al.
Publicado: (2012)

Correction: Correction: The role of cortical oscillations in a spiking neural network model of the basal ganglia
Publicado: (2020)

A Diffusive Homeostatic Signal Maintains Neural Heterogeneity and Responsiveness in Cortical Networks
por: Sweeney, Yann, et al.
Publicado: (2015)

Altered Basal Ganglia Network Integration in Schizophrenia
por: Duan, Mingjun, et al.
Publicado: (2015)

The mouse cortico–basal ganglia–thalamic network
por: Foster, Nicholas N., et al.
Publicado: (2021)

Untangle network security
por: El-Bawab, Abd El-Monem A
Publicado: (2014)

A Computational Model of Dual Competition between the Basal Ganglia and the Cortex
por: Topalidou, Meropi, et al.
Publicado: (2019)

Learning to Select Actions with Spiking Neurons in the Basal Ganglia
por: Stewart, Terrence C., et al.
Publicado: (2012)

Dopamine Depletion Affects Vocal Acoustics and Disrupts Sensorimotor Adaptation in Songbirds
por: Saravanan, Varun, et al.
Publicado: (2019)

Transient Calcium and Dopamine Increase PKA Activity and DARPP-32 Phosphorylation
por: Lindskog, Maria, et al.
Publicado: (2006)

A Common Function of Basal Ganglia-Cortical Circuits Subserving Speed in Both Motor and Cognitive Domains
por: Hanakawa, Takashi, et al.
Publicado: (2017)

Opponent Learning with Different Representations in the Cortico-Basal Ganglia Circuits
por: Morita, Kenji, et al.
Publicado: (2023)

A Connectomic Analysis of the Human Basal Ganglia Network
por: Cacciola, Alberto, et al.
Publicado: (2017)

A network model of basal ganglia for understanding the roles of dopamine and serotonin in reward-punishment-risk based decision making
por: Balasubramani, Pragathi P., et al.
Publicado: (2015)

Dopaminergic and Cholinergic Modulation of Large Scale Networks in silico Using Snudda
por: Frost Nylen, Johanna, et al.
Publicado: (2021)

Role of Beta-Arrestin 2 Downstream of Dopamine Receptors in the Basal Ganglia
por: Del’Guidice, Thomas, et al.
Publicado: (2011)

Feasibility of dopamine as a vector-valued feedback signal in the basal ganglia
por: Wärnberg, Emil, et al.
Publicado: (2023)

Dynamic reorganization of the cortico-basal ganglia-thalamo-cortical network during task learning
por: Sych, Yaroslav, et al.
Publicado: (2022)

A biologically constrained spiking neural network model of the primate basal ganglia with overlapping pathways exhibits action selection
por: Girard, Benoît, et al.
Publicado: (2020)

Untangling the Interplay between Epidemic Spread and Transmission Network Dynamics
por: Kamp, Christel
Publicado: (2010)

The effect of spike time dependent plasticity on activity patterns in the basal ganglia
por: Lourens, Marcel AJ, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_t2nbpgp627b0mmocdiqoha1iu6