Cargando…

Predicting and validating microRNA targets

Given that microRNAs select their targets by nucleotide base-pairing, it follows that it should be possible to find microRNA targets computationally. There has been considerable progress, but assessing success and biological significance requires a move into the 'wet' lab.

Detalles Bibliográficos
Autor principal: Lai, Eric C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC522861/
https://www.ncbi.nlm.nih.gov/pubmed/15345038
http://dx.doi.org/10.1186/gb-2004-5-9-115
_version_ 1782121864131248128
author Lai, Eric C
author_facet Lai, Eric C
author_sort Lai, Eric C
collection PubMed
description Given that microRNAs select their targets by nucleotide base-pairing, it follows that it should be possible to find microRNA targets computationally. There has been considerable progress, but assessing success and biological significance requires a move into the 'wet' lab.
format Text
id pubmed-522861
institution National Center for Biotechnology Information
language English
publishDate 2004
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-5228612004-10-17 Predicting and validating microRNA targets Lai, Eric C Genome Biol Opinion Given that microRNAs select their targets by nucleotide base-pairing, it follows that it should be possible to find microRNA targets computationally. There has been considerable progress, but assessing success and biological significance requires a move into the 'wet' lab. BioMed Central 2004 2004-08-31 /pmc/articles/PMC522861/ /pubmed/15345038 http://dx.doi.org/10.1186/gb-2004-5-9-115 Text en Copyright © 2004 BioMed Central Ltd
spellingShingle Opinion
Lai, Eric C
Predicting and validating microRNA targets
title Predicting and validating microRNA targets
title_full Predicting and validating microRNA targets
title_fullStr Predicting and validating microRNA targets
title_full_unstemmed Predicting and validating microRNA targets
title_short Predicting and validating microRNA targets
title_sort predicting and validating microrna targets
topic Opinion
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC522861/
https://www.ncbi.nlm.nih.gov/pubmed/15345038
http://dx.doi.org/10.1186/gb-2004-5-9-115
work_keys_str_mv AT laiericc predictingandvalidatingmicrornatargets