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Predicting and validating microRNA targets
Given that microRNAs select their targets by nucleotide base-pairing, it follows that it should be possible to find microRNA targets computationally. There has been considerable progress, but assessing success and biological significance requires a move into the 'wet' lab.
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2004
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC522861/ https://www.ncbi.nlm.nih.gov/pubmed/15345038 http://dx.doi.org/10.1186/gb-2004-5-9-115 |
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author | Lai, Eric C |
author_facet | Lai, Eric C |
author_sort | Lai, Eric C |
collection | PubMed |
description | Given that microRNAs select their targets by nucleotide base-pairing, it follows that it should be possible to find microRNA targets computationally. There has been considerable progress, but assessing success and biological significance requires a move into the 'wet' lab. |
format | Text |
id | pubmed-522861 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2004 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-5228612004-10-17 Predicting and validating microRNA targets Lai, Eric C Genome Biol Opinion Given that microRNAs select their targets by nucleotide base-pairing, it follows that it should be possible to find microRNA targets computationally. There has been considerable progress, but assessing success and biological significance requires a move into the 'wet' lab. BioMed Central 2004 2004-08-31 /pmc/articles/PMC522861/ /pubmed/15345038 http://dx.doi.org/10.1186/gb-2004-5-9-115 Text en Copyright © 2004 BioMed Central Ltd |
spellingShingle | Opinion Lai, Eric C Predicting and validating microRNA targets |
title | Predicting and validating microRNA targets |
title_full | Predicting and validating microRNA targets |
title_fullStr | Predicting and validating microRNA targets |
title_full_unstemmed | Predicting and validating microRNA targets |
title_short | Predicting and validating microRNA targets |
title_sort | predicting and validating microrna targets |
topic | Opinion |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC522861/ https://www.ncbi.nlm.nih.gov/pubmed/15345038 http://dx.doi.org/10.1186/gb-2004-5-9-115 |
work_keys_str_mv | AT laiericc predictingandvalidatingmicrornatargets |