Brief Report: Switching to Tenofovir Alafenamide, Coformulated With Elvitegravir, Cobicistat, and Emtricitabine, in HIV-Infected Adults With Renal Impairment: 96-Week Results From a Single-Arm, Multicenter, Open-Label Phase 3 Study

Tenofovir disoproxil fumarate is associated with renal and bone toxicity. In a single-arm, open-label study of 242 virologically suppressed, HIV-infected participants with creatinine clearance 30–69 mL/min who switched to elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide, participants had...

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Detalles Bibliográficos
Autores principales: Post, Frank A., Tebas, Pablo, Clarke, Amanda, Cotte, Laurent, Short, William R., Abram, Michael E., Jiang, Shuping, Cheng, Andrew, Das, Moupali, Fordyce, Marshall W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JAIDS Journal of Acquired Immune Deficiency Syndromes 2017
Materias:
Clinical Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5228610/
https://www.ncbi.nlm.nih.gov/pubmed/27673443
http://dx.doi.org/10.1097/QAI.0000000000001186

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