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Burn injury during long-term oxygen therapy in Denmark and Sweden: the potential role of smoking

BACKGROUND: Long-term oxygen therapy (LTOT) increases life expectancy in patients with COPD and severe hypoxemia. Smoking is the main cause of burn injury during LTOT. Policy regarding smoking while on LTOT varies between countries. In this study, we compare the incidence of burn injury that require...

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Autores principales: Tanash, Hanan A, Ringbaek, Thomas, Huss, Fredrik, Ekström, Magnus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5230731/
https://www.ncbi.nlm.nih.gov/pubmed/28123292
http://dx.doi.org/10.2147/COPD.S119949
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author Tanash, Hanan A
Ringbaek, Thomas
Huss, Fredrik
Ekström, Magnus
author_facet Tanash, Hanan A
Ringbaek, Thomas
Huss, Fredrik
Ekström, Magnus
author_sort Tanash, Hanan A
collection PubMed
description BACKGROUND: Long-term oxygen therapy (LTOT) increases life expectancy in patients with COPD and severe hypoxemia. Smoking is the main cause of burn injury during LTOT. Policy regarding smoking while on LTOT varies between countries. In this study, we compare the incidence of burn injury that required contact with a health care specialist, between Sweden (a country with a strict policy regarding smoking while on LTOT) and Denmark (a country with less strict smoking policy). METHODS: This was a population-based, cohort study of patients initiating LTOT due to any cause in Sweden and Denmark. Data on diagnoses, external causes, and procedures were obtained from the Swedish and Danish National Patient Registers for inpatient and outpatient care. Patients were followed from January 1, 2000, until the first of the following: LTOT withdrawal, death, or study end (December 31, 2009). The primary end point was burn injury during LTOT. RESULTS: A total of 23,741 patients received LTOT in Denmark and 7,754 patients in Sweden. Most patients started LTOT due to COPD, both in Sweden (74%) and in Denmark (62%). The rate of burn injury while on LTOT was higher in Denmark than in Sweden; 170 (95% confidence interval [CI], 126–225) vs 85 (95% CI, 44–148) per 100,000 person-years; rate ratio 2.0 (95% CI, 1.0–4.1). The risk remained higher after adjustment for gender, age, and diagnosis in multivariate Cox regression, hazard ratio 1.8 (95% CI, 1.0−3.5). Thirty-day mortality after burn injury was 8% in both countries. CONCLUSION: Compared to Sweden, the rate of burn injury was twice as high in Denmark where smoking is not a contraindication for prescribing LTOT.
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spelling pubmed-52307312017-01-25 Burn injury during long-term oxygen therapy in Denmark and Sweden: the potential role of smoking Tanash, Hanan A Ringbaek, Thomas Huss, Fredrik Ekström, Magnus Int J Chron Obstruct Pulmon Dis Original Research BACKGROUND: Long-term oxygen therapy (LTOT) increases life expectancy in patients with COPD and severe hypoxemia. Smoking is the main cause of burn injury during LTOT. Policy regarding smoking while on LTOT varies between countries. In this study, we compare the incidence of burn injury that required contact with a health care specialist, between Sweden (a country with a strict policy regarding smoking while on LTOT) and Denmark (a country with less strict smoking policy). METHODS: This was a population-based, cohort study of patients initiating LTOT due to any cause in Sweden and Denmark. Data on diagnoses, external causes, and procedures were obtained from the Swedish and Danish National Patient Registers for inpatient and outpatient care. Patients were followed from January 1, 2000, until the first of the following: LTOT withdrawal, death, or study end (December 31, 2009). The primary end point was burn injury during LTOT. RESULTS: A total of 23,741 patients received LTOT in Denmark and 7,754 patients in Sweden. Most patients started LTOT due to COPD, both in Sweden (74%) and in Denmark (62%). The rate of burn injury while on LTOT was higher in Denmark than in Sweden; 170 (95% confidence interval [CI], 126–225) vs 85 (95% CI, 44–148) per 100,000 person-years; rate ratio 2.0 (95% CI, 1.0–4.1). The risk remained higher after adjustment for gender, age, and diagnosis in multivariate Cox regression, hazard ratio 1.8 (95% CI, 1.0−3.5). Thirty-day mortality after burn injury was 8% in both countries. CONCLUSION: Compared to Sweden, the rate of burn injury was twice as high in Denmark where smoking is not a contraindication for prescribing LTOT. Dove Medical Press 2017-01-05 /pmc/articles/PMC5230731/ /pubmed/28123292 http://dx.doi.org/10.2147/COPD.S119949 Text en © 2017 Tanash et al. This work is published and licensed by Dove Medical Press Limited The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Original Research
Tanash, Hanan A
Ringbaek, Thomas
Huss, Fredrik
Ekström, Magnus
Burn injury during long-term oxygen therapy in Denmark and Sweden: the potential role of smoking
title Burn injury during long-term oxygen therapy in Denmark and Sweden: the potential role of smoking
title_full Burn injury during long-term oxygen therapy in Denmark and Sweden: the potential role of smoking
title_fullStr Burn injury during long-term oxygen therapy in Denmark and Sweden: the potential role of smoking
title_full_unstemmed Burn injury during long-term oxygen therapy in Denmark and Sweden: the potential role of smoking
title_short Burn injury during long-term oxygen therapy in Denmark and Sweden: the potential role of smoking
title_sort burn injury during long-term oxygen therapy in denmark and sweden: the potential role of smoking
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5230731/
https://www.ncbi.nlm.nih.gov/pubmed/28123292
http://dx.doi.org/10.2147/COPD.S119949
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