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The Power of Malaria Vaccine Trials Using Controlled Human Malaria Infection
Controlled human malaria infection (CHMI) in healthy human volunteers is an important and powerful tool in clinical malaria vaccine development. However, power calculations are essential to obtain meaningful estimates of protective efficacy, while minimizing the risk of adverse events. To optimize p...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5230743/ https://www.ncbi.nlm.nih.gov/pubmed/28081133 http://dx.doi.org/10.1371/journal.pcbi.1005255 |