Cutaneous Deficiency of Filaggrin and STAT3 Exacerbates Vaccinia Disease In Vivo

RATIONALE: Defects in filaggrin and STAT3 are associated with atopic dermatitis (AD) and susceptibility to severe skin infection. METHODS: We evaluated skin infection with the current smallpox vaccine, ACAM-2000, in immunosuppressed mice with combined cutaneous deficiency in filaggrin and STAT3. In...

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Detalles Bibliográficos
Autores principales: He, Yong, Sultana, Ishrat, Takeda, Kazuyo, Reed, Jennifer L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5231274/
https://www.ncbi.nlm.nih.gov/pubmed/28081250
http://dx.doi.org/10.1371/journal.pone.0170070

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5231274/
https://www.ncbi.nlm.nih.gov/pubmed/28081250
http://dx.doi.org/10.1371/journal.pone.0170070

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