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Cutaneous Deficiency of Filaggrin and STAT3 Exacerbates Vaccinia Disease In Vivo
RATIONALE: Defects in filaggrin and STAT3 are associated with atopic dermatitis (AD) and susceptibility to severe skin infection. METHODS: We evaluated skin infection with the current smallpox vaccine, ACAM-2000, in immunosuppressed mice with combined cutaneous deficiency in filaggrin and STAT3. In...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5231274/ https://www.ncbi.nlm.nih.gov/pubmed/28081250 http://dx.doi.org/10.1371/journal.pone.0170070 |