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Collective Genetic Interaction Effects and the Role of Antigen-Presenting Cells in Autoimmune Diseases
Autoimmune diseases occur when immune cells fail to develop or lose their tolerance toward self and destroy body’s own tissues. Both insufficient negative selection of self-reactive T cells and impaired development of regulatory T cells preventing effector cell activation are believed to contribute...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5231276/ https://www.ncbi.nlm.nih.gov/pubmed/28081217 http://dx.doi.org/10.1371/journal.pone.0169918 |