Cargando…
An Alpha-1A Adrenergic Receptor Agonist Prevents Acute Doxorubicin Cardiomyopathy in Male Mice
Alpha-1 adrenergic receptors mediate adaptive effects in the heart and cardiac myocytes, and a myocyte survival pathway involving the alpha-1A receptor subtype and ERK activation exists in vitro. However, data in vivo are limited. Here we tested A61603 (N-[5-(4,5-dihydro-1H-imidazol-2-yl)-2-hydroxy-...
Autores principales: | Montgomery, Megan D., Chan, Trevor, Swigart, Philip M., Myagmar, Bat-erdene, Dash, Rajesh, Simpson, Paul C. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5231318/ https://www.ncbi.nlm.nih.gov/pubmed/28081170 http://dx.doi.org/10.1371/journal.pone.0168409 |
Ejemplares similares
-
The Alpha-1A Adrenergic Receptor in the Rabbit Heart
por: Thomas, R. Croft, et al.
Publicado: (2016) -
Cardiac magnetic resonance of targeted annexin-iron oxide labeling detects cardiac cell death in vivo after doxorubicin and myocardial infarction
por: Dash, Rajesh, et al.
Publicado: (2009) -
A Myocardial Slice Culture Model Reveals Alpha-1A-Adrenergic Receptor Signaling in the Human Heart
por: Thomas, R. Croft, et al.
Publicado: (2016) -
Functional alpha-1B adrenergic receptors on human epicardial coronary artery endothelial cells
por: Jensen, Brian C., et al.
Publicado: (2010) -
An Oral Selective Alpha-1A Adrenergic Receptor Agonist Prevents Doxorubicin Cardiotoxicity
por: Beak, Ju Youn, et al.
Publicado: (2017)