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Par3 integrates Tiam1 and phosphatidylinositol 3-kinase signaling to change apical membrane identity
Pathogens can alter epithelial polarity by recruiting polarity proteins to the apical membrane, but how a change in protein localization is linked to polarity disruption is not clear. In this study, we used chemically induced dimerization to rapidly relocalize proteins from the cytosol to the apical...
Autores principales: | Ruch, Travis R., Bryant, David M., Mostov, Keith E., Engel, Joanne N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5231894/ https://www.ncbi.nlm.nih.gov/pubmed/27881661 http://dx.doi.org/10.1091/mbc.E16-07-0541 |
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