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Par3 integrates Tiam1 and phosphatidylinositol 3-kinase signaling to change apical membrane identity

Pathogens can alter epithelial polarity by recruiting polarity proteins to the apical membrane, but how a change in protein localization is linked to polarity disruption is not clear. In this study, we used chemically induced dimerization to rapidly relocalize proteins from the cytosol to the apical...

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Detalles Bibliográficos
Autores principales: Ruch, Travis R., Bryant, David M., Mostov, Keith E., Engel, Joanne N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5231894/
https://www.ncbi.nlm.nih.gov/pubmed/27881661
http://dx.doi.org/10.1091/mbc.E16-07-0541

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