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How and why intralumenal membrane fragments form during vacuolar lysosome fusion

Lysosomal membrane fusion mediates the last step of the autophagy and endocytosis pathways and supports organelle remodeling and biogenesis. Because fusogenic proteins and lipids concentrate in a ring at the vertex between apposing organelle membranes, the encircled area of membrane can be severed a...

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Detalles Bibliográficos
Autores principales: Mattie, Sevan, McNally, Erin K., Karim, Mahmoud A., Vali, Hojatollah, Brett, Christopher L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5231899/
https://www.ncbi.nlm.nih.gov/pubmed/27881666
http://dx.doi.org/10.1091/mbc.E15-11-0759