Sustained Subconjunctival Delivery of Infliximab Protects the Cornea and Retina Following Alkali Burn to the Eye

PURPOSE: Tumor necrosis factor (TNF)-α is upregulated in eyes following corneal alkali injury and contributes to corneal and also retinal damage. Prompt TNF-α inhibition by systemic infliximab ameliorates retinal damage and improves corneal wound healing. However, systemic administration of TNF-α in...

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Detalles Bibliográficos
Autores principales: Zhou, Chengxin, Robert, Marie-Claude, Kapoulea, Vassiliki, Lei, Fengyang, Stagner, Anna M., Jakobiec, Frederick A., Dohlman, Claes H., Paschalis, Eleftherios I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2017
Materias:
Cornea
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5231904/
https://www.ncbi.nlm.nih.gov/pubmed/28114570
http://dx.doi.org/10.1167/iovs.16-20339

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