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A Systematic Framework for Drug Repositioning from Integrated Omics and Drug Phenotype Profiles Using Pathway-Drug Network

Drug repositioning offers new clinical indications for old drugs. Recently, many computational approaches have been developed to repurpose marketed drugs in human diseases by mining various of biological data including disease expression profiles, pathways, drug phenotype expression profiles, and ch...

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Detalles Bibliográficos
Autores principales: Jadamba, Erkhembayar, Shin, Miyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5233404/
https://www.ncbi.nlm.nih.gov/pubmed/28127549
http://dx.doi.org/10.1155/2016/7147039