Vitamin C and l-Proline Antagonistic Effects Capture Alternative States in the Pluripotency Continuum

Metabolites and cofactors are emerging as key regulators of cell plasticity and reprogramming, and their role in the control of pluripotency is just being discovered. Here we provide unprecedented evidence that embryonic stem cell (ESC) pluripotency relies on the relative levels of two physiological...

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Detalles Bibliográficos
Autores principales: D'Aniello, Cristina, Habibi, Ehsan, Cermola, Federica, Paris, Debora, Russo, Francesco, Fiorenzano, Alessandro, Di Napoli, Gabriele, Melck, Dominique J., Cobellis, Gilda, Angelini, Claudia, Fico, Annalisa, Blelloch, Robert, Motta, Andrea, Stunnenberg, Hendrik G., De Cesare, Dario, Patriarca, Eduardo J., Minchiotti, Gabriella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5233408/
https://www.ncbi.nlm.nih.gov/pubmed/28017658
http://dx.doi.org/10.1016/j.stemcr.2016.11.011

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