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Non-Lethal Endotoxin Injection: A Rat Model of Hypercoagulability
Systemic inflammation co-activates coagulation, which unchecked culminates in a lethal syndrome of multi-organ microvascular thrombosis known as disseminated intravascular coagulation (DIC). We studied an endotoxin-induced inflammatory state in rats to identify biomarkers of hemostatic imbalance fav...
Autores principales: | Brooks, Marjory B., Turk, James R., Guerrero, Abraham, Narayanan, Padma K., Nolan, John P., Besteman, Elizabeth G., Wilson, Dennis W., Thomas, Roberta A., Fishman, Cindy E., Thompson, Karol L., Ellinger-Ziegelbauer, Heidrun, Pierson, Jennifer B., Paulman, April, Chiang, Alan Y., Schultze, Albert E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5233421/ https://www.ncbi.nlm.nih.gov/pubmed/28081568 http://dx.doi.org/10.1371/journal.pone.0169976 |
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