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LRRK2 enhances Nod1/2-mediated inflammatory cytokine production by promoting Rip2 phosphorylation

The innate immune system is critical for clearing infection, and is tightly regulated to avert excessive tissue damage. Nod1/2-Rip2 signaling, which is essential for initiating the innate immune response to bacterial infection and ER stress, is subject to many regulatory mechanisms. In this study, w...

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Detalles Bibliográficos
Autores principales: Yan, Ruiqing, Liu, Zhihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5233611/
https://www.ncbi.nlm.nih.gov/pubmed/27830463
http://dx.doi.org/10.1007/s13238-016-0326-x

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