HCN channel dendritic targeting requires bipartite interaction with TRIP8b and regulates antidepressant-like behavioral effects

Major Depressive Disorder is a prevalent psychiatric condition with limited therapeutic options beyond monoaminergic therapies. Although effective in some individuals, many patients fail to respond adequately to existing treatments and new pharmacologic targets are needed. HCN channels regulate exci...

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Detalles Bibliográficos
Autores principales: Han, Ye, Heuermann, Robert J., Lyman, Kyle A., Fisher, Daniel, Ismail, Quratul-Ain, Chetkovich, Dane M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5233690/
https://www.ncbi.nlm.nih.gov/pubmed/27400855
http://dx.doi.org/10.1038/mp.2016.99

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5233690/
https://www.ncbi.nlm.nih.gov/pubmed/27400855
http://dx.doi.org/10.1038/mp.2016.99

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