Prolonged fibroblast growth factor 19 response in patients with primary sclerosing cholangitis after an oral chenodeoxycholic acid challenge

BACKGROUND: Bile salts likely contribute to liver injury in patients with primary sclerosing cholangitis (PSC) and primary biliary cholangitis (PBC). Fibroblast growth factor 19 (FGF19) is a bile salt-induced enterokine with hepatoprotective potential as it suppresses de novo bile salt synthesis. He...

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Detalles Bibliográficos
Autores principales: Zweers, Serge J., de Vries, Elisabeth M., Lenicek, Martin, Tolenaars, Dagmar, de Waart, D. Rudi, Koelfat, Kiran V. K., Groen, Albert K., Olde Damink, Steven W. M., Beuers, Ulrich, Ponsioen, Cyriel, Jansen, Peter L. M., Schaap, Frank G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer India 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5233735/
https://www.ncbi.nlm.nih.gov/pubmed/27696157
http://dx.doi.org/10.1007/s12072-016-9769-7

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