7-ketocholesterol induces apoptosis of MC3T3-E1 cells associated with reactive oxygen species generation, endoplasmic reticulum stress and caspase-3/7 dependent pathway

Type 2 diabetes mellitus (T2DM) is associated with an increased risk of bone fractures without reduction of bone mineral density. The cholesterol oxide 7-ketocholesterol (7KCHO) has been implicated in numerous diseases such as atherosclerosis, Alzheimer's disease, Parkinson's disease, canc...

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Detalles Bibliográficos
Autores principales: Sato, Yuta, Ishihara, Noriko, Nagayama, Daiji, Saiki, Atsuhito, Tatsuno, Ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5233792/
https://www.ncbi.nlm.nih.gov/pubmed/28116245
http://dx.doi.org/10.1016/j.ymgmr.2017.01.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5233792/
https://www.ncbi.nlm.nih.gov/pubmed/28116245
http://dx.doi.org/10.1016/j.ymgmr.2017.01.006

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