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Paternal Insulin-like Growth Factor 2 (Igf2) Regulates Stem Cell Activity During Adulthood

Insulin-like Growth Factor 2 (IGF2) belongs to the IGF/Insulin pathway, a highly conserved evolutionarily network that regulates growth, aging and lifespan. Igf2 is highly expressed in the embryo and in cancer cells. During mouse development, Igf2 is expressed in all sites where hematopoietic stem c...

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Detalles Bibliográficos
Autores principales: Barroca, Vilma, Lewandowski, Daniel, Jaracz-Ros, Agnieszka, Hardouin, Sylvie-Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5233811/
https://www.ncbi.nlm.nih.gov/pubmed/28007480
http://dx.doi.org/10.1016/j.ebiom.2016.11.035