Chronic Over-expression of Fibroblast Growth Factor 21 Increases Bile Acid Biosynthesis by Opposing FGF15/19 Action

Pharmacological doses of fibroblast growth factor (FGF) 21 effectively normalize glucose, lipid and energy homeostasis in multiple animal models with many benefits translating to obese humans with type 2 diabetes. However, a role for FGF21 in the regulation of bile acid metabolism has not been repor...

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Detalles Bibliográficos
Autores principales: Zhang, Jun, Gupte, Jamila, Gong, Yan, Weiszmann, Jennifer, Zhang, Yuan, Lee, Ki Jeong, Richards, William G., Li, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5233823/
https://www.ncbi.nlm.nih.gov/pubmed/28041926
http://dx.doi.org/10.1016/j.ebiom.2016.12.016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5233823/
https://www.ncbi.nlm.nih.gov/pubmed/28041926
http://dx.doi.org/10.1016/j.ebiom.2016.12.016

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