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Regulation of XIAP Turnover Reveals a Role for USP11 in Promotion of Tumorigenesis

The emerging regulatory role of deubiquitinases (DUBs) has been implicated in various fundamental processes and pathogenesis. To determine the pivotal role that DUBs play in mediating tumorigenesis, we have performed a non-biased screen of 67 human DUBs based on a mammary cell transformation assay....

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Detalles Bibliográficos
Autores principales: Zhou, Zhuan, Luo, Aiping, Shrivastava, Indira, He, Mingjing, Huang, Yi, Bahar, Ivet, Liu, Zhihua, Wan, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5233825/
https://www.ncbi.nlm.nih.gov/pubmed/28040451
http://dx.doi.org/10.1016/j.ebiom.2016.12.014