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Regulation of XIAP Turnover Reveals a Role for USP11 in Promotion of Tumorigenesis
The emerging regulatory role of deubiquitinases (DUBs) has been implicated in various fundamental processes and pathogenesis. To determine the pivotal role that DUBs play in mediating tumorigenesis, we have performed a non-biased screen of 67 human DUBs based on a mammary cell transformation assay....
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5233825/ https://www.ncbi.nlm.nih.gov/pubmed/28040451 http://dx.doi.org/10.1016/j.ebiom.2016.12.014 |