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Fluorescence assay of dihydroorotate dehydrogenase that may become a cancer biomarker

We developed an assay method for measuring dihydroorotate dehydrogenase (DHODH) activity in cultured HeLa cells and fibroblasts, and in stage III stomach cancer and adjacent normal tissues from the same patient. The assay comprised enzymatic reaction of DHODH with a large amount of dihydroorotic aci...

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Detalles Bibliográficos
Autores principales:	Yin, Sheng, Kabashima, Tsutomu, Zhu, Qinchang, Shibata, Takayuki, Kai, Masaaki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5233952/ https://www.ncbi.nlm.nih.gov/pubmed/28084471 http://dx.doi.org/10.1038/srep40670

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