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Single PA mutation as a high yield determinant of avian influenza vaccines
Human infection with an avian influenza virus persists. To prepare for a potential outbreak of avian influenza, we constructed a candidate vaccine virus (CVV) containing hemagglutinin (HA) and neuraminidase (NA) genes of a H5N1 virus and evaluated its antigenic stability after serial passaging in em...
Autores principales: | Lee, Ilseob, Il Kim, Jin, Park, Sehee, Bae, Joon-Yong, Yoo, Kirim, Yun, Soo-Hyeon, Lee, Joo-Yeon, Kim, Kisoon, Kang, Chun, Park, Man-Seong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5233958/ https://www.ncbi.nlm.nih.gov/pubmed/28084423 http://dx.doi.org/10.1038/srep40675 |
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