Neuronal sFlt1 and Vegfaa determine venous sprouting and spinal cord vascularization

Formation of organ-specific vasculatures requires cross-talk between developing tissue and specialized endothelial cells. Here we show how developing zebrafish spinal cord neurons coordinate vessel growth through balancing of neuron-derived Vegfaa, with neuronal sFlt1 restricting Vegfaa-Kdrl mediate...

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Detalles Bibliográficos
Autores principales: Wild, Raphael, Klems, Alina, Takamiya, Masanari, Hayashi, Yuya, Strähle, Uwe, Ando, Koji, Mochizuki, Naoki, van Impel, Andreas, Schulte-Merker, Stefan, Krueger, Janna, Preau, Laetitia, le Noble, Ferdinand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5234075/
https://www.ncbi.nlm.nih.gov/pubmed/28071661
http://dx.doi.org/10.1038/ncomms13991

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