Integrating mass spectrometry with MD simulations reveals the role of lipids in Na(+)/H(+) antiporters

Na(+)/H(+) antiporters are found in all kingdoms of life and exhibit catalysis rates that are among the fastest of all known secondary-active transporters. Here we combine ion mobility mass spectrometry and molecular dynamics simulations to study the conformational stability and lipid-binding proper...

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Detalles Bibliográficos
Autores principales: Landreh, Michael, Marklund, Erik G., Uzdavinys, Povilas, Degiacomi, Matteo T., Coincon, Mathieu, Gault, Joseph, Gupta, Kallol, Liko, Idlir, Benesch, Justin L. P., Drew, David, Robinson, Carol V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5234078/
https://www.ncbi.nlm.nih.gov/pubmed/28071645
http://dx.doi.org/10.1038/ncomms13993

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