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Mannose-binding lectin-associated serine protease 2 (MASP-2) contributes to poor disease outcome in humans and mice with pneumococcal meningitis

BACKGROUND: Pneumococcal meningitis is the most common and severe form of bacterial meningitis. Fatality rates are substantial, and long-term sequelae develop in about half of survivors. Disease outcome has been related to the severity of the pro-inflammatory response in the subarachnoid space. The...

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Detalles Bibliográficos
Autores principales:	Kasanmoentalib, E. Soemirien, Valls Seron, Mercedes, Ferwerda, Bart, Tanck, Michael W., Zwinderman, Aeilko H., Baas, Frank, van der Ende, Arie, Brouwer, Matthijs C., van de Beek, Diederik
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5234106/ https://www.ncbi.nlm.nih.gov/pubmed/28086930 http://dx.doi.org/10.1186/s12974-016-0770-9

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