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Modeling sRNA-Regulated Plasmid Maintenance

We study a theoretical model for the toxin-antitoxin (hok/sok) mechanism for plasmid maintenance in bacteria. Toxin-antitoxin systems enforce the maintenance of a plasmid through post-segregational killing of cells that have lost the plasmid. Key to their function is the tight regulation of expressi...

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Detalles Bibliográficos
Autores principales: Gong, Chen Chris, Klumpp, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5234814/
https://www.ncbi.nlm.nih.gov/pubmed/28085919
http://dx.doi.org/10.1371/journal.pone.0169703

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