RNA Sequencing Reveals that Kaposi Sarcoma-Associated Herpesvirus Infection Mimics Hypoxia Gene Expression Signature

Kaposi sarcoma-associated herpesvirus (KSHV) causes several tumors and hyperproliferative disorders. Hypoxia and hypoxia-inducible factors (HIFs) activate latent and lytic KSHV genes, and several KSHV proteins increase the cellular levels of HIF. Here, we used RNA sequencing, qRT-PCR, Taqman assays,...

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Detalles Bibliográficos
Autores principales: Viollet, Coralie, Davis, David A., Tekeste, Shewit S., Reczko, Martin, Ziegelbauer, Joseph M., Pezzella, Francesco, Ragoussis, Jiannis, Yarchoan, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5234848/
https://www.ncbi.nlm.nih.gov/pubmed/28046107
http://dx.doi.org/10.1371/journal.ppat.1006143

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5234848/
https://www.ncbi.nlm.nih.gov/pubmed/28046107
http://dx.doi.org/10.1371/journal.ppat.1006143

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