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Targeted Inhibition of Pancreatic Acinar Cell Calcineurin Is a Novel Strategy to Prevent Post-ERCP Pancreatitis
BACKGROUND & AIMS: There is a pressing need to develop effective preventative therapies for post–endoscopic retrograde cholangiopancreatography pancreatitis (PEP). We showed that early PEP events are induced through the calcium-activated phosphatase calcineurin and that global calcineurin deleti...
Autores principales: | Orabi, Abrahim I., Wen, Li, Javed, Tanveer A., Le, Tianming, Guo, Ping, Sanker, Subramaniam, Ricks, David, Boggs, Kristy, Eisses, John F., Castro, Carlos, Xiao, Xiangwei, Prasadan, Krishna, Esni, Farzad, Gittes, George K., Husain, Sohail Z. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5235344/ https://www.ncbi.nlm.nih.gov/pubmed/28090570 http://dx.doi.org/10.1016/j.jcmgh.2016.08.006 |
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