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Targeted Inhibition of Pancreatic Acinar Cell Calcineurin Is a Novel Strategy to Prevent Post-ERCP Pancreatitis

BACKGROUND & AIMS: There is a pressing need to develop effective preventative therapies for post–endoscopic retrograde cholangiopancreatography pancreatitis (PEP). We showed that early PEP events are induced through the calcium-activated phosphatase calcineurin and that global calcineurin deleti...

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Detalles Bibliográficos
Autores principales: Orabi, Abrahim I., Wen, Li, Javed, Tanveer A., Le, Tianming, Guo, Ping, Sanker, Subramaniam, Ricks, David, Boggs, Kristy, Eisses, John F., Castro, Carlos, Xiao, Xiangwei, Prasadan, Krishna, Esni, Farzad, Gittes, George K., Husain, Sohail Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5235344/
https://www.ncbi.nlm.nih.gov/pubmed/28090570
http://dx.doi.org/10.1016/j.jcmgh.2016.08.006

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