Progression of transsynaptic retinal degeneration with spectral-domain optical coherence tomography

PURPOSE: To illustrate the progression of retrograde transsynaptic retinal degeneration using spectral-domain optical coherence tomography (SD-OCT). OBSERVATIONS: A 60 year-old man with a stroke was followed over a 17-month period using SD-OCT of the macula, ganglion cell layer (GCC), and retinal ne...

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Detalles Bibliográficos
Autores principales: Schwartz, Stephen G., Monroig, Armando, Flynn, Harry W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Case report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5235357/
https://www.ncbi.nlm.nih.gov/pubmed/28093579
http://dx.doi.org/10.1016/j.ajoc.2016.12.010
Descripción
Sumario:PURPOSE: To illustrate the progression of retrograde transsynaptic retinal degeneration using spectral-domain optical coherence tomography (SD-OCT). OBSERVATIONS: A 60 year-old man with a stroke was followed over a 17-month period using SD-OCT of the macula, ganglion cell layer (GCC), and retinal nerve fiber layer. Transsynaptic retinal degeneration progressed over this time. CONCLUSIONS AND IMPORTANCE: Retrograde transsynaptic retinal degeneration may occur in patients with homonymous visual field loss caused by post-geniculate neurologic disease. This is best detected as homonymous thinning of the retina, corresponding to the pattern of visual field loss, using SD-OCT of the GCC and macula. The retinal changes occur at a variable time following the onset of neurologic disease.

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