Bcl-xL Affects Group A Streptococcus-Induced Autophagy Directly, by Inhibiting Fusion between Autophagosomes and Lysosomes, and Indirectly, by Inhibiting Bacterial Internalization via Interaction with Beclin 1-UVRAG

Anti-apoptotic Bcl-2 and Bcl-xL are proposed to regulate starvation-induced autophagy by directly interacting with Beclin 1. Beclin 1 is also thought to be involved in multiple vesicle trafficking pathways such as endocytosis by binding to Atg14L and UVRAG. However, how the interaction of Bcl-2 fami...

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Detalles Bibliográficos
Autores principales: Nakajima, Shintaro, Aikawa, Chihiro, Nozawa, Takashi, Minowa-Nozawa, Atsuko, Toh, Hirotaka, Nakagawa, Ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5235370/
https://www.ncbi.nlm.nih.gov/pubmed/28085926
http://dx.doi.org/10.1371/journal.pone.0170138

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5235370/
https://www.ncbi.nlm.nih.gov/pubmed/28085926
http://dx.doi.org/10.1371/journal.pone.0170138

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